IGF-1 LR3 research: overview and resources
What IGF-1 LR3 research material is, how it is characterized, and where to find every specification, method, lot record and reference IGF-1 LR3 Labs publishes about it.
What is IGF-1 LR3?
IGF-1 LR3 (Long R3 IGF-1) is an 83-residue analog of insulin-like growth factor 1. It differs from the 70-residue native IGF-1 in two ways: a 13-residue extension (MFPAMPLSSLFVN) at the N-terminus, and arginine in place of glutamate at position 3 of the IGF-1 sequence, which is the "R3" in the name. Both changes greatly reduce binding to IGF-binding proteins while leaving the IGF-1 receptor (IGF1R) binding region intact, which is why the analog is widely used in cell-culture research.
IGF-1 LR3 Labs supplies it as a lyophilized powder in 1 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity against a reference standard and net content, with a fentanyl screen, and the certificate is published here before sale through Klow.bio.
What is IGF-1 LR3 research material?
IGF-1 LR3 research material is IGF-1 LR3 supplied for laboratory research (C400H619N111O115S9, 9111.55 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is IGF-1 LR3 characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 99.69%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
IGF-1 LR3 at a glance
- Product
- IGF-1 LR3
- Type
- 83-residue IGF-1 analog, 83 residues
- Also known as
- Long R3 IGF-1, LR3-IGF-I
- Receptor design
- IGF-1 receptor (IGF1R)
- Molecular formula
- C400H619N111O115S9
- Molecular weight
- 9111.55 g/mol (average)
- Form
- Lyophilized powder
- Vial sizes
- 1 mg
- Purity, current lots
- 99.69% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by HPLC retention-time match on every lot
- Testing laboratory
- ILS Laboratories (independent)
- Current lot
- KB-17790, reported Sep 11, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
IGF-1 LR3 research resources
Every IGF-1 LR3 resource on igf1lr3.bio, organized from chemistry to documentation.
IGF-1 LR3 specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of IGF-1 LR3
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a IGF-1 LR3 COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any IGF-1 LR3 lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a IGF-1 LR3 certificate.
Research materialIGF-1 LR3 research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- NCBI Gene: IGF1 (insulin like growth factor 1). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/3479
- NCBI Gene: IGF1R (insulin like growth factor 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/3480
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
IGF-1 LR3 Labs analytical documentation
- Lot KB-17790: 1 mg, 99.69% purity, reported Sep 11, 2026
- IGF-1 LR3 testing records (all tests, all lots; CSV available)
Editorial scope
IGF-1 LR3 Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy IGF-1 LR3
1 mg vials. Current lot KB-17790 tested at 99.69% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.